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neflb


Official Full Name
neurofilament light chain b
Organism
Danio rerio
Gene ID
664698
Background
Predicted to be a structural constituent of postsynaptic intermediate filament cytoskeleton. Acts upstream of or within hindbrain development; negative regulation of neuron apoptotic process; and spinal cord development. Predicted to be located in cell projection. Predicted to be active in axon; cytoplasm; and intermediate filament cytoskeleton. Is expressed in nervous system. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease (multiple); amyotrophic lateral sclerosis; and invasive ductal carcinoma. Orthologous to human NEFL (neurofilament light chain). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
nefl; zgc:136626

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