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MVK


Official Full Name
mevalonate kinase
Organism
Homo sapiens
Gene ID
4598
Background
This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Synonyms
MK; LRBP; MVLK; POROK3

Cat.No. Product Name Price
SHH209423 shRNA set against Human MVK(NM_000431.2) Inquiry
SHH209431 shRNA set against Mouse Mvk(NM_023556.2) Inquiry
SHH209449 shRNA set against Rat Mvk(NM_031063.1) Inquiry
SHH347256 shRNA set against Human MVK (NM_000431.2) Inquiry
SHH347260 shRNA set against Mouse MVK (NM_023556.2) Inquiry
SHH347264 shRNA set against Rat MVK (NM_031063.1) Inquiry
SHW007624 shRNA set against Danio rerio MVK (NM_001007349) Inquiry
Cat.No. Product Name Price
CDFH011963 Human MVK cDNA Clone(NM_001114185.1) Inquiry
CDFR012538 Rat Mvk cDNA Clone(NM_031063.1) Inquiry
MiUTR1H-06539 MVK miRNA 3'UTR clone Inquiry
MiUTR1M-07408 MVK miRNA 3'UTR clone Inquiry
MiUTR3H-02479 MVK miRNA 3'UTR clone Inquiry
CDCB159542 Human MVK ORF clone (BC016140) Inquiry
CDCB169099 Danio rerio MVK ORF Clone (NM_001007349) Inquiry
CDCB193417 Rabbit MVK ORF clone (XM_008251372.1) Inquiry
CDCL135515 Mouse Mvk ORF clone (NM_023556.2) Inquiry
CDCR348063 Human MVK ORF Clone(NM_001114185.1) Inquiry
CDCR379560 Rat Mvk ORF Clone(NM_031063.1) Inquiry
CDCS405658 Human MVK ORF Clone (BC016140) Inquiry
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