Pages
Products

MUS81


Official Full Name
MUS81 structure-specific endonuclease subunit
Organism
Homo sapiens
Gene ID
80198
Background
This gene encodes a structure-specific endonuclease which belongs to the XPF/MUS81 endonuclease family and plays a critical role in the resolution of recombination intermediates during DNA repair after inter-strand cross-links, replication fork collapse, and DNA double-strand breaks. The encoded protein associates with one of two closely related essential meiotic endonuclease proteins (EME1 or EME2) to form a complex that processes DNA secondary structures. It contains an N-terminal DEAH helicase domain, an excision repair cross complementation group 4 (ERCC4) endonuclease domain, and two tandem C-terminal helix-hairpin-helix domains. Mice with a homozygous knockout of the orthologous gene have significant meiotic defects including the failure to repair a subset of DNA double strand breaks. [provided by RefSeq, Jun 2017]
Synonyms
SLX3

Cat.No. Product Name Price
SHH347180 shRNA set against Rat MUS81 (NM_001025645.1) Inquiry
SHH208937 shRNA set against Rat Mus81(NM_001025645.1) Inquiry
SHH208973 shRNA set against Human MUS81(NM_025128.4) Inquiry
SHH347172 shRNA set against Human MUS81 (NM_025128.4) Inquiry
SHH347176 shRNA set against Mouse MUS81 (NM_027877.3) Inquiry
SHW018563 shRNA set against Danio rerio MUS81 (NM_213518) Inquiry
Cat.No. Product Name Price
CDFR004000 Rat Mus81 cDNA Clone(NM_001025645.1) Inquiry
MiUTR1H-06533 MUS81 miRNA 3'UTR clone Inquiry
MiUTR1R-04059 MUS81 miRNA 3'UTR clone Inquiry
CDCB158718 Human MUS81 ORF clone (BC009999) Inquiry
CDCB180038 Danio rerio MUS81 ORF Clone (NM_213518) Inquiry
CDCB192707 Rabbit MUS81 ORF clone (XM_008252036.1) Inquiry
CDCL135455 Mouse MUS81 ORF clone (NM_025128.4) Inquiry
CDCR260644 Mouse Mus81 ORF Clone(NM_027877.3) Inquiry
CDCR370977 Rat Mus81 ORF Clone(NM_001025645.1) Inquiry
CDCS415905 Human MUS81 ORF Clone (BC009999) Inquiry
Quick Inquiry