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MRC2

Official Full Name
mannose receptor C-type 2
Organism
Homo sapiens
GeneID
9902
Background
This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease. [provided by RefSeq, Feb 2012]
Synonyms
CD280; UPARAP; CLEC13E; ENDO180;

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