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MMP7


Official Full Name
matrix metallopeptidase 7
Organism
Homo sapiens
Gene ID
4316
Background
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers. [provided by RefSeq, Jan 2016]
Synonyms
MMP-7; MPSL1; PUMP-1

Cat.No. Product Name Price
AD10040Z Human MMP7 adenoviral particles Inquiry
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SHH194141 shRNA set against Rat Mmp7(NM_012864.2) Inquiry
SHH194159 shRNA set against Human MMP7(NM_002423.3) Inquiry
SHH194177 shRNA set against Mouse Mmp7(NM_010810.4) Inquiry
SHH343108 shRNA set against Human MMP7 (NM_002423.3) Inquiry
SHH343112 shRNA set against Mouse MMP7 (NM_010810.4) Inquiry
SHH343116 shRNA set against Rat MMP7 (NM_012864.2) Inquiry
SHW000367 shRNA set against Chicken MMP7 (NM_001006278) Inquiry
Cat.No. Product Name Price
CDFR010720 Rat Mmp7 cDNA Clone(NM_012864.2) Inquiry
MiUTR1H-06362 MMP7 miRNA 3'UTR clone Inquiry
MiUTR1M-07183 MMP7 miRNA 3'UTR clone Inquiry
MiUTR1R-03950 MMP7 miRNA 3'UTR clone Inquiry
CDCB161842 Chicken MMP7 ORF Clone (NM_001006278) Inquiry
CDCB183123 Rabbit MMP7 ORF clone (XM_002708573.2) Inquiry
CDCR377723 Rat Mmp7 ORF Clone(NM_012864.2) Inquiry
CDCS410784 Human MMP7 ORF Clone (BC003635) Inquiry
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