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MLLT11


Official Full Name
MLLT11 transcription factor 7 cofactor
Organism
Homo sapiens
Gene ID
10962
Background
The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1;11)(q21;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested. [provided by RefSeq, Jul 2008]
Synonyms
AF1Q

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Cat.No. Product Name Price
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CDFR002991 Rat Mllt11 cDNA Clone(NM_001013912.1) Inquiry
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CDCB186177 Rabbit MLLT11 ORF clone (XM_008264056.1) Inquiry
CDCH390131 Mouse MLLT11 ORF clone(NM_019914.4) Inquiry
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