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MBD1


Official Full Name
methyl-CpG binding domain protein 1
Organism
Homo sapiens
Gene ID
4152
Background
The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions; several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides; transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Feb 2011]
Synonyms
RFT; PCM1; CXXC3

Cat.No. Product Name Price
SHH179111 shRNA set against Rat Mbd1(NM_001011924.1) Inquiry
SHH179129 shRNA set against Human MBD1(NM_002384.2) Inquiry
SHH179165 shRNA set against Human MBD1(NM_015844.2) Inquiry
SHH179183 shRNA set against Human MBD1(NM_015846.3) Inquiry
SHH179201 shRNA set against Human MBD1(NM_015845.3) Inquiry
SHH179219 shRNA set against Human MBD1(NM_015847.3) Inquiry
SHH338743 shRNA set against Human MBD1 (NM_015844.2) Inquiry
SHH338751 shRNA set against Rat MBD1 (NM_001011924.1) Inquiry
Cat.No. Product Name Price
SKO0145 MBD1 Validated sgRNA vector Inquiry
MiUTR3H-01412 MBD1 miRNA 3'UTR clone Inquiry
MiUTR1H-06130 MBD1 miRNA 3'UTR clone Inquiry
MiUTR1H-06129 MBD1 miRNA 3'UTR clone Inquiry
MiUTR1H-06128 MBD1 miRNA 3'UTR clone Inquiry
CDFR002354 Rat Mbd1 cDNA Clone(NM_001011924.1) Inquiry
MiUTR3H-01415 MBD1 miRNA 3'UTR clone Inquiry
CDCR369441 Rat Mbd1 ORF Clone(NM_001011924.1) Inquiry
CDCL130999 Human MBD1 ORF clone (NM_001204136.1) Inquiry
CDCL130995 Mouse MBD1 ORF clone (NM_001204143.1) Inquiry
CDCL130993 Human MBD1 ORF clone (NM_015847.3) Inquiry
CDCL130991 Mouse MBD1 ORF clone (NM_015846.3) Inquiry
CDCL130989 Mouse MBD1 ORF clone (NM_015845.3) Inquiry
CDCL130987 Mouse MBD1 ORF clone (NM_002384.2) Inquiry
CDCL130979 Human MBD1 ORF clone (NM_001204141.1) Inquiry
CDCL130997 Human MBD1 ORF clone (NM_001204142.1) Inquiry
CDCB193496 Rabbit MBD1 ORF clone (XM_008261298.1) Inquiry
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