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MAPKBP1


Official Full Name
mitogen-activated protein kinase binding protein 1
Organism
Homo sapiens
Gene ID
23005
Background
This gene encodes a scaffold protein that regulates the JNK (c-Jun N-terminal kinase) and NOD2 (nucleotide-binding oligomerization domain-containing protein 2) signaling pathways. The encoded protein interacts with another related JNK pathway scaffold protein, WDR62, via a conserved dimerization domain, and enhances JNK signaling. This protein may play a role in bacterial immunity by binding to the NOD2 receptor and negatively regulating downstream antibacterial and pro-inflammatory signaling. Mutations in this gene that impair cellular localization of the encoded protein cause a form of nephronophthisis, an autosomal-recessive kidney disorder, in human patients. [provided by RefSeq, May 2017]
Synonyms
JNKBP1; NPHP20; JNKBP-1

Cat.No. Product Name Price
SHH176627 shRNA set against Human MAPKBP1(NM_001128608.1) Inquiry
SHH176663 shRNA set against Human MAPKBP1(NM_001265611.1) Inquiry
SHH338183 shRNA set against Human MAPKBP1 (NM_014994.2) Inquiry
SHH338187 shRNA set against Mouse MAPKBP1 (NM_011941.3) Inquiry
SHH338191 shRNA set against Rat MAPKBP1 (NM_001108589.1) Inquiry
Cat.No. Product Name Price
CDFH011065 Human MAPKBP1 cDNA Clone(NM_001128608.1) Inquiry
CDFR008183 Rat Mapkbp1 cDNA Clone(NM_001108589.1) Inquiry
MiUTR1H-06103 MAPKBP1 miRNA 3'UTR clone Inquiry
MiUTR1H-06104 MAPKBP1 miRNA 3'UTR clone Inquiry
MiUTR4H-TG05360 MAPKBP1 miRNA 3'UTR clone Inquiry
CDCB192293 Rabbit MAPKBP1 ORF clone (XM_008269139.1) Inquiry
CDCL130599 Human MAPKBP1 ORF clone (NM_001128608.1) Inquiry
CDCR251615 Mouse Mapkbp1 ORF Clone(NM_011941.3) Inquiry
CDCR375196 Rat Mapkbp1 ORF Clone(NM_001108589.1) Inquiry
CDCS407852 Human MAPKBP1 ORF Clone (BC114493) Inquiry
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