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MAP3K7


Official Full Name
mitogen-activated protein kinase kinase kinase 7
Organism
Homo sapiens
Gene ID
6885
Background
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Synonyms
CSCF; FMD2; TAK1; MEKK7; TGF1a

Cat.No. Product Name Price
AD09631Z Human MAP3K7 adenoviral particles Inquiry
Cat.No. Product Name Price
SHH337743 shRNA set against Human MAP3K7 (NM_003188.3) Inquiry
SHH337747 shRNA set against Mouse MAP3K7 (NM_172688.3) Inquiry
SHH337751 shRNA set against Rat MAP3K7 (NM_001107920.2) Inquiry
SHW008776 shRNA set against Danio rerio MAP3K7 (NM_001020750) Inquiry
Cat.No. Product Name Price
CDFL007353 Mouse Map3k7 cDNA Clone(NM_172688.3) Inquiry
CDFR007565 Rat Map3k7 cDNA Clone(NM_001107920.2) Inquiry
MiUTR3H-05126 MAP3K7 miRNA 3'UTR clone Inquiry
MiUTR3H-05127 MAP3K7 miRNA 3'UTR clone Inquiry
MiUTR3H-05128 MAP3K7 miRNA 3'UTR clone Inquiry
MiUTR3H-05129 MAP3K7 miRNA 3'UTR clone Inquiry
SKO0583 MAP3K7 Validated sgRNA vector Inquiry
CDCB170251 Danio rerio MAP3K7 ORF Clone (NM_001020750) Inquiry
CDCB191582 Rabbit MAP3K7 ORF clone (XM_002714585.2) Inquiry
CDCR247008 Mouse Map3k7 ORF Clone(NM_009316.1) Inquiry
CDCR271466 Mouse Map3k7 ORF Clone(NM_172688.3) Inquiry
CDCR374588 Rat Map3k7 ORF Clone(NM_001107920.2) Inquiry
CDCS411186 Human MAP3K7 ORF Clone (BC017715) Inquiry
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