Pages
Products

LEFTY2


Official Full Name
left-right determination factor 2
Organism
Homo sapiens
Gene ID
7044
Background
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. This gene is closely linked to both a related family member and a related pseudogene. This gene encodes multiple isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016]
Synonyms
EBAF; LEFTA; TGFB4; LEFTYA

Cat.No. Product Name Price
SHH329483 shRNA set against Mouse LEFTY2 (NM_177099.3) Inquiry
SHH145919 shRNA set against Mouse Lefty2(NM_177099.3) Inquiry
SHH329479 shRNA set against Human LEFTY2 (NM_003240.3) Inquiry
SHH329487 shRNA set against Rat LEFTY2 (NM_001007556.1) Inquiry
SHW005271 shRNA set against Chicken LEFTY2 (NM_204764) Inquiry
Cat.No. Product Name Price
CDCB166746 Chicken LEFTY2 ORF Clone (NM_204764) Inquiry
CDFH010293 Human LEFTY2 cDNA Clone(NM_001172425.1) Inquiry
CDFR001606 Rat Lefty2 cDNA Clone(NM_001007556.1) Inquiry
MiUTR1M-06592 LEFTY2 miRNA 3'UTR clone Inquiry
MiUTR3H-04472 LEFTY2 miRNA 3'UTR clone Inquiry
CDCL126739 Mouse Lefty2 ORF clone (NM_177099.3) Inquiry
CDCL185124 Rat LEFTY2 ORF clone(NM_001007556.1) Inquiry
CDCR356514 Human LEFTY2 ORF Clone(NM_001172425.1) Inquiry
CDCS411203 Human LEFTY2 ORF Clone (BC035718) Inquiry
Quick Inquiry