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LEPR


Official Full Name
leptin receptor
Organism
Homo sapiens
Gene ID
3953
Background
The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010]
Synonyms
OBR; OB-R; CD295; LEP-R; LEPRD

Cat.No. Product Name Price
SHH146675 shRNA set against Mouse Leprot(NM_175036.4) Inquiry
SHH146711 shRNA set against Rat Leprot(NM_020099.2) Inquiry
SHH329619 shRNA set against Human Lepr (NM_002303.5) Inquiry
SHW008414 shRNA set against Danio rerio LEPROT (NM_001017787) Inquiry
SHH146459 shRNA set against Rat Lepr(NM_012596.1) Inquiry
SHH329623 shRNA set against Mouse Lepr (NM_010704.2) Inquiry
SHH329627 shRNA set against Rat Lepr (NM_012596.1) Inquiry
SHH329675 shRNA set against Human LEPROT (NM_001198681.1) Inquiry
SHH329679 shRNA set against Mouse LEPROT (NM_175036.4) Inquiry
SHH329683 shRNA set against Rat LEPROT (NM_001013188.2) Inquiry
SHW000751 shRNA set against Chicken LEPROT (NM_001007958) Inquiry
SHW004839 shRNA set against Chicken LEPR (NM_204323) Inquiry
SHW012170 shRNA set against Danio rerio LEPR (NM_001113376) Inquiry
Cat.No. Product Name Price
MiUTR4H-TG05029 LEPROT miRNA 3'UTR clone Inquiry
MiUTR1R-02986 LEPROT miRNA 3'UTR clone Inquiry
MiUTR1R-02983 LEPR miRNA 3'UTR clone Inquiry
MiUTR1M-06604 LEPROT miRNA 3'UTR clone Inquiry
CDFR011659 Rat Leprot cDNA Clone(NM_020099.2) Inquiry
CDFR010415 Rat Lepr cDNA Clone(NM_012596.1) Inquiry
CDCL126809 Mouse LEPR ORF clone (NM_001198688.1) Inquiry
CDCL126811 Human LEPR ORF clone (NM_002303.5) Inquiry
CDFL006911 Mouse Lepr cDNA Clone(NM_146146.2) Inquiry
CDCL126851 Human LEPROT ORF clone (NM_001198683.1) Inquiry
CDFL006910 Mouse Lepr cDNA Clone(NM_010704.2) Inquiry
CDCR008160 Mouse LEPROT ORF clone(NM_175036.4) Inquiry
CDFG019367 Mouse Lepr cDNA Clone(NM_001122899.1) Inquiry
MiUTR3H-03798 LEPR miRNA 3'UTR clone Inquiry
CDCS418905 Human LEPROT ORF Clone (BC056250) Inquiry
CDCR378706 Rat Leprot ORF Clone(NM_020099.2) Inquiry
CDCR268075 Mouse Lepr ORF Clone(NM_146146.2) Inquiry
CDCR338884 Human LEPR ORF Clone(NM_001003679.3) Inquiry
CDCR249429 Mouse Lepr ORF Clone(NM_010704.2) Inquiry
CDCL126853 Human LEPROT ORF clone (NM_001198681.1) Inquiry
CDCL126813 Human Lepr ORF clone (NM_001122899.1) Inquiry
CDCB186718 Rabbit LEPR ORF clone (XM_008265109.1) Inquiry
CDCB184755 Rabbit LEPROT ORF clone (XM_002715941.2) Inquiry
CDCB173645 Danio rerio LEPR ORF Clone (NM_001113376) Inquiry
CDCB169889 Danio rerio LEPROT ORF Clone (NM_001017787) Inquiry
CDCB166314 Chicken LEPR ORF Clone (NM_204323) Inquiry
CDCR377462 Rat Lepr ORF Clone(NM_012596.1) Inquiry
CDCB162226 Chicken LEPROT ORF Clone (NM_001007958) Inquiry
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