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KDELR2


Official Full Name
KDEL endoplasmic reticulum protein retention receptor 2
Organism
Homo sapiens
Gene ID
11014
Background
Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR2 was the second member of the family to be identified, and it encodes a protein which is 83% identical to the KDELR1 gene product. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Synonyms
ELP1; OI21; ELP-1; ERD2.2

Cat.No. Product Name Price
SHH324107 shRNA set against Human KDELR2 (NM_006854.3) Inquiry
SHH324111 shRNA set against Mouse KDELR2 (NM_025841.4) Inquiry
SHH324115 shRNA set against Rat KDELR2 (NM_001013122.1) Inquiry
SHL193688 shRNA set against Human KDELR2(NM_006854.3) Inquiry
SHL193706 shRNA set against Rat Kdelr2(NM_001013122.1) Inquiry
SHW002893 shRNA set against Chicken KDELR2 (NM_001159715) Inquiry
Cat.No. Product Name Price
CDCS412951 Human KDELR2 ORF Clone (BC012994) Inquiry
CDCS412953 Human KDELR2 ORF Clone (BC071982) Inquiry
CDFH009720 Human KDELR2 cDNA Clone(NM_001100603.1) Inquiry
CDFR002848 Rat Kdelr2 cDNA Clone(NM_001013122.1) Inquiry
MiUTR1H-05186 KDELR2 miRNA 3'UTR clone Inquiry
MiUTR1R-02855 KDELR2 miRNA 3'UTR clone Inquiry
MiUTR3H-10371 KDELR2 miRNA 3'UTR clone Inquiry
SKO0553 KDELR2 Validated sgRNA vector Inquiry
CDCB164368 Chicken KDELR2 ORF Clone (NM_001159715) Inquiry
CDCB194305 Rabbit KDELR2 ORF clone (XM_002723361.2) Inquiry
CDCR347181 Human KDELR2 ORF Clone(NM_001100603.1) Inquiry
CDCR369847 Rat Kdelr2 ORF Clone(NM_001013122.1) Inquiry
CDCS412952 Human KDELR2 ORF Clone (BC008081) Inquiry
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