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IL12RB2


Official Full Name
interleukin 12 receptor subunit beta 2
Organism
Homo sapiens
Gene ID
3595
Background
The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene. [provided by RefSeq, Apr 2012]
Synonyms
gals2b; lgals1l3; Drgal1-L3; zgc:66283

Cat.No. Product Name Price
SHL171300 shRNA set against Mouse Il12rb2(NM_008354.3) Inquiry
SHL171318 shRNA set against Human IL12RB2(NM_001559.2) Inquiry
SHW003949 shRNA set against Chicken IL12RB2 (NM_001277627) Inquiry
SHW012190 shRNA set against Danio rerio IL12RB2 (NM_001113505) Inquiry
Cat.No. Product Name Price
CDCL120163 Human IL12RB2 ORF clone (NM_001258216.1) Inquiry
CDCL184755 Rat IL12RB2 ORF clone(NM_001191750.1) Inquiry
CDFH009141 Human IL12RB2 cDNA Clone(NM_001559.2) Inquiry
MiUTR1H-04873 IL12RB2 miRNA 3'UTR clone Inquiry
MiUTR1M-05969 IL12RB2 miRNA 3'UTR clone Inquiry
CDCB156493 Canine IL12RB2 ORF clone (NM_001025399.1) Inquiry
CDCB165424 Chicken IL12RB2 ORF Clone (NM_001277627) Inquiry
CDCB173665 Danio rerio IL12RB2 ORF Clone (NM_001113505) Inquiry
CDCB187652 Rabbit IL12RB2 ORF clone (XM_008265082.1) Inquiry
CDCL120159 Mouse IL12RB2 ORF clone (NM_001258214.1) Inquiry
CDCL120161 Mouse IL12RB2 ORF clone (NM_001258215.1) Inquiry
CDCL184753 Human IL12Rb2 ORF clone(NM_001559.2) Inquiry
CDCL184754 Mouse IL12RB2 ORF clone(NM_008354.3) Inquiry
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