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IDH2


Official Full Name
isocitrate dehydrogenase (NADP(+)) 2
Organism
Homo sapiens
Gene ID
3418
Background
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Synonyms
IDH; IDP; IDHM; IDPM; ICD-M; IDH-2; D2HGA2; mNADP-IDH

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SHW002181 shRNA set against Chicken IDH2 (NM_001031599) Inquiry
SHH316569 shRNA set against Human IDH2 (NM_002168.2) Inquiry
SHH316573 shRNA set against Mouse IDH2 (NM_173011.2) Inquiry
SHH316577 shRNA set against Rat IDH2 (NM_001014161.1) Inquiry
SHW015853 shRNA set against Danio rerio IDH2 (NM_199564) Inquiry
Cat.No. Product Name Price
CDFH008957 Human IDH2 cDNA Clone(NM_002168.2) Inquiry
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MiUTR1R-03220 IDH2 miRNA 3'UTR clone Inquiry
CDCB159042 Human IDH2 ORF clone (BC009244) Inquiry
CDCB163656 Chicken IDH2 ORF Clone (NM_001031599) Inquiry
CDCB177328 Danio rerio IDH2 ORF Clone (NM_199564) Inquiry
CDCB193151 Rabbit IDH2 ORF clone (XM_002721491.2) Inquiry
CDCR271988 Mouse Idh2 ORF Clone(NM_173011.2) Inquiry
CDCR282546 Human IDH2 ORF Clone(NM_002168.2) Inquiry
CDCR370295 Rat Idh2 ORF Clone(NM_001014161.1) Inquiry
CDCS410662 Human IDH2 ORF Clone (BC009244) Inquiry
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