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HRAS


Official Full Name
HRas proto-oncogene, GTPase
Organism
Homo sapiens
Gene ID
3265
Background
This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, cognitive disability, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008]
Synonyms
CTLO; HAMSV; HRAS1; RASH1; p21ras; C-H-RAS; H-RASIDX; C-BAS/HAS; C-HA-RAS1

Cat.No. Product Name Price
SHW005787 shRNA set against Chicken HRAS (NM_205292) Inquiry
SHH314769 shRNA set against Human HRAS (NM_005343.2) Inquiry
SHH314773 shRNA set against Mouse HRAS (NM_025731.2) Inquiry
SHH314777 shRNA set against Rat HRAS (NM_001098241.1) Inquiry
Cat.No. Product Name Price
CDCL184609 Human HRAS ORF clone(NM_001130442.1) Inquiry
CDFH008765 Human HRAS cDNA Clone(NM_001130442.1) Inquiry
CDFH008766 Human HRAS cDNA Clone(NM_005343.2) Inquiry
CDFR005156 Rat Hras cDNA Clone(NM_001098241.1) Inquiry
MiUTR1H-04691 HRAS miRNA 3'UTR clone Inquiry
MiUTR3H-02267 HRAS miRNA 3'UTR clone Inquiry
MiUTR3H-02269 HRAS miRNA 3'UTR clone Inquiry
CDCB167262 Chicken HRAS ORF Clone (NM_205292) Inquiry
CDCR289899 Human HRAS ORF Clone(NM_005343.2) Inquiry
CDCR372197 Rat Hras ORF Clone(NM_001098241.1) Inquiry
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