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H2-ab1


Official Full Name
histocompatibility 2, class II antigen A, beta 1
Organism
Mus musculus
Gene ID
14961
Background
Enables peptide antigen binding activity. Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II and immune response. Located in Golgi apparatus; endosome; and external side of plasma membrane. Part of MHC class II protein complex. Is expressed in several structures, including adipose tissue; bone; hemolymphoid system; liver; and lung. Used to study dilated cardiomyopathy and myocarditis. Human ortholog(s) of this gene implicated in several diseases, including allergic disease (multiple); autoimmune disease (multiple); bacterial infectious disease (multiple); hematologic cancer (multiple); and liver disease (multiple). Orthologous to several human genes including HLA-DQB1 (major histocompatibility complex, class II, DQ beta 1). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
H2-Ab1; IAb; Ia2; Ia-2; Abeta; H-2Ab; H2-Ab; Rmcs1; I-Abeta

Cat.No. Product Name Price
SHH309790 shRNA set against Mouse H2-Ab1 (NM_207105.3) Inquiry
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SHH309794 shRNA set against Human H2AFB1 (NM_001017990.1) Inquiry
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SHH309802 shRNA set against Human H2AFB2 (NM_001017991.1) Inquiry
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Cat.No. Product Name Price
CDFG007403 Human H2AFB3 cDNA Clone(NM_080720.1) Inquiry
CDFH008250 Human H2AFB1 cDNA Clone(NM_001017990.1) Inquiry
CDFH008251 Human H2AFB2 cDNA Clone(NM_001017991.1) Inquiry
CDFR006683 Rat H2afb3 cDNA Clone(NM_001106969.1) Inquiry
MiUTR1H-04347 H2AFB1 miRNA 3'UTR clone Inquiry
MiUTR1H-04348 H2AFB2 miRNA 3'UTR clone Inquiry
MiUTR1M-00255 H2AFB1 miRNA 3'UTR clone Inquiry
MiUTR4H-TG11395 H2AFB3 miRNA 3'UTR clone Inquiry
CDCB158011 Human H2AFB3 ORF clone (BC101415) Inquiry
CDCL112479 Mouse Gm14920 ORF clone (NM_001102665.1) Inquiry
CDCL115781 Mouse H2AFB1 ORF clone (NM_001017990.1) Inquiry
CDCR315180 Human H2AFB3 ORF Clone(NM_080720.1) Inquiry
CDCR341967 Human H2AFB2 ORF Clone(NM_001017991.1) Inquiry
CDCR373745 Rat H2afb3 ORF Clone(NM_001106969.1) Inquiry
CDCS416670 Human H2AFB3 ORF Clone (BC101415) Inquiry
CDCS418658 Human H2AFB1 ORF Clone (BC128034) Inquiry
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