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GIF

Official Full Name
macrophage migration inhibitory factor
Organism
Homo sapiens
GeneID
4282
Background
This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. [provided by RefSeq, Jul 2008]
Synonyms
MIF; GIF; GLIF; MMIF;

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