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GUCY2D


Official Full Name
guanylate cyclase 2D, retinal
Organism
Homo sapiens
Gene ID
3000
Background
This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. [provided by RefSeq, Dec 2008]
Synonyms
LCA; CACD; CG-E; CYGD; LCA1; RCD2; CACD1; CORD5; CORD6; GUC2D; ROSGC; retGC; CSNB1I; GUC1A4; RETGC-1; ROS-GC1

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SHH309378 shRNA set against Human GUCY2D (NM_000180.3) Inquiry
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CDCB191269 Rabbit GUCY2D ORF clone (XM_008270763.1) Inquiry
CDCR237546 Mouse Gucy2d ORF Clone(NM_001130693.2) Inquiry
CDCR380944 Rat Gucy2d ORF Clone(NM_130737.4) Inquiry
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