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GPER


Official Full Name
G protein-coupled estrogen receptor 1
Organism
Homo sapiens
Gene ID
2852
Background
This gene encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum and a member of the G-protein coupled receptor 1 family. This receptor binds estrogen and activates multiple downstream signaling pathways, leading to stimulation of adenylate cyclase and an increase in cyclic AMP levels, while also promoting intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. This receptor has been shown to play a role in diverse biological processes, including bone and nervous system development, metabolism, cognition, male fertility and uterine function. [provided by RefSeq, Aug 2017]
Synonyms
GPER1; mER; CEPR; GPER; DRY12; FEG-1; GPR30; LERGU; LyGPR; CMKRL2; LERGU2; GPCR-Br

Cat.No. Product Name Price
SHH305854 shRNA set against Human GPER (NM_001505.2) Inquiry
Cat.No. Product Name Price
CDFH007835 Human GPER cDNA Clone(NM_001039966.1) Inquiry
CDFH007836 Human GPER cDNA Clone(NM_001098201.1) Inquiry
CDFR014090 Rat Gper cDNA Clone(NM_133573.1) Inquiry
MiUTR1H-04211 GPER miRNA 3'UTR clone Inquiry
MiUTR1R-02243 GPER miRNA 3'UTR clone Inquiry
MiUTR3H-04426 GPER miRNA 3'UTR clone Inquiry
MiUTR3H-04427 GPER miRNA 3'UTR clone Inquiry
CDCL184452 Human GPER ORF clone(NM_001039966.1) Inquiry
CDCR346428 Human GPER ORF Clone(NM_001098201.1) Inquiry
CDCR381145 Rat Gper ORF Clone(NM_133573.1) Inquiry
CDCS406997 Human GPER ORF Clone (BC011634) Inquiry
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