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GPI


Official Full Name
glucose-6-phosphate isomerase
Organism
Homo sapiens
Gene ID
2821
Background
This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phosphate and fructose-6-phosphate. Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion. The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
Synonyms
AMF; NLK; PGI; PHI; GNPI; SA36; SA-36; CNSHA4

Cat.No. Product Name Price
SHH096437 shRNA set against Rat Gpi(NM_207592.1) Inquiry
SHH305054 shRNA set against Human GNPDA1 (NM_005471.4) Inquiry
SHH305058 shRNA set against Mouse GNPDA1 (NM_011937.2) Inquiry
SHH305898 shRNA set against Human GPI (NM_000175.3) Inquiry
SHH305902 shRNA set against Mouse GPI (NM_026730.1) Inquiry
SHH305906 shRNA set against Rat GPI (NM_207592.1) Inquiry
SHH305910 shRNA set against Mouse Gpi1 (NM_008155.3) Inquiry
SHW000222 shRNA set against Chicken GPI (NM_001006128) Inquiry
SHW000250 shRNA set against Chicken GNPDA1 (NM_001006156) Inquiry
SHW008475 shRNA set against Danio rerio GNPDA1 (NM_001017867) Inquiry
SHW015289 shRNA set against Danio rerio GPIA (NM_144763) Inquiry
SHW015290 shRNA set against Danio rerio GPIB (NM_144764) Inquiry
Cat.No. Product Name Price
MiUTR3H-04423 GNPDA1 miRNA 3'UTR clone Inquiry
MiUTR1R-02214 GPI miRNA 3'UTR clone Inquiry
CDCB161725 Chicken GNPDA1 ORF Clone (NM_001006156) Inquiry
CDFR015341 Rat Gpi cDNA Clone(NM_207592.1) Inquiry
CDFR010089 Rat Gnpda1 cDNA Clone(NM_001134995.1) Inquiry
CDFH007840 Human GPI cDNA Clone(NM_001184722.1) Inquiry
MiUTR3H-01736 GPI miRNA 3'UTR clone Inquiry
CDCS412279 Human GNPDA1 ORF Clone (BC020769) Inquiry
CDCS412278 Human GNPDA1 ORF Clone (BC001717) Inquiry
CDCS412277 Human GNPDA1 ORF Clone (BC012853) Inquiry
CDCR382417 Rat Gpi ORF Clone(NM_207592.1) Inquiry
CDCR377130 Rat Gnpda1 ORF Clone(NM_001134995.1) Inquiry
CDCR251607 Mouse Gnpda1 ORF Clone(NM_011937.2) Inquiry
CDCL184454 Human GPI ORF clone(NM_024816.2) Inquiry
CDCL113683 Human GPI ORF clone (NM_001184722.1) Inquiry
CDCB184412 Rabbit GNPDA1 ORF clone (XM_008255154.1) Inquiry
CDCB180438 Rabbit GPI ORF clone (NM_001082069.2) Inquiry
CDCB176765 Danio rerio GPIB ORF Clone (NM_144764) Inquiry
CDCB176764 Danio rerio GPIA ORF Clone (NM_144763) Inquiry
CDCB169950 Danio rerio GNPDA1 ORF Clone (NM_001017867) Inquiry
CDCB161697 Chicken GPI ORF Clone (NM_001006128) Inquiry
CDCR244981 Mouse Gpi1 ORF Clone(NM_008155.3) Inquiry
CDCB158882 Human GNPDA1 ORF clone (BC012853) Inquiry
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