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GALNT1


Official Full Name
polypeptide N-acetylgalactosaminyltransferase 1
Organism
Homo sapiens
Gene ID
2589
Background
This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. Transcript variants derived from this gene that utilize alternative polyA signals have been described in the literature. [provided by RefSeq, Jul 2008]
Synonyms
GALNAC-T1

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LV13337L human GALNT1 (NM_020474) lentivirus particles Inquiry
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CDCL110451 Mouse Galnt1 ORF clone (NM_001160404.1) Inquiry
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