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FAM111A


Official Full Name
FAM111 trypsin like peptidase A
Organism
Homo sapiens
Gene ID
63901
Background
The protein encoded by this gene is cell-cycle regulated, and has nuclear localization. The C-terminal half of the protein shares homology with trypsin-like peptidases and it contains a PCNA-interacting peptide (PIP) box, that is necessary for its co-localization with proliferating cell nuclear antigen (PCNA). Reduced expression of this gene resulted in DNA replication defects, consistent with the demonstrated role for this gene in Simian Virus 40 (SV40) viral replication. Mutations in this gene have been associated with Kenny-Caffey syndrome (KCS) type 2 and the more severe osteocraniostenosis (OCS, also known as Gracile Bone Dysplasia), both characterized by short stature, hypoparathyroidism, bone development abnormalities, and hypocalcemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
Synonyms
KCS2; GCLEB

Cat.No. Product Name Price
SHH289121 shRNA set against Human FAM111A (NM_198847.2) Inquiry
SHH289125 shRNA set against Mouse FAM111A (NM_026640.2) Inquiry
Cat.No. Product Name Price
CDCR062400 Human FAM111A ORF clone (NM_001142519.1) Inquiry
CDCR351414 Human FAM111A ORF Clone(NM_001142520.1) Inquiry
CDFH006315 Human FAM111A cDNA Clone(NM_001142519.1) Inquiry
CDFH006316 Human FAM111A cDNA Clone(NM_001142521.1) Inquiry
CDFH006317 Human FAM111A cDNA Clone(NM_001142520.1) Inquiry
CDFR008708 Rat Fam111a cDNA Clone(NM_001109163.1) Inquiry
MiUTR1M-00583 FAM111A miRNA 3'UTR clone Inquiry
MiUTR3H-14794 FAM111A miRNA 3'UTR clone Inquiry
MiUTR3H-14795 FAM111A miRNA 3'UTR clone Inquiry
MiUTR3H-14796 FAM111A miRNA 3'UTR clone Inquiry
MiUTR3H-14797 FAM111A miRNA 3'UTR clone Inquiry
MiUTR3H-14798 FAM111A miRNA 3'UTR clone Inquiry
CDCB190439 Rabbit FAM111A ORF clone (XM_008271656.1) Inquiry
CDCR259040 Mouse Fam111a ORF Clone(NM_026640.2) Inquiry
CDCR351416 Human FAM111A ORF Clone(NM_001142521.1) Inquiry
CDCR375795 Rat Fam111a ORF Clone(NM_001109163.1) Inquiry
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