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MPZL2


Official Full Name
myelin protein zero like 2
Organism
Homo sapiens
Gene ID
10205
Background
Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ. Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. This gene is expressed in the thymus and in several epithelial structures early in embryogenesis. It is highly homologous to the myelin protein zero and, in thymus-derived epithelial cell lines, is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis. The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain; a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
EVA; EVA1; DFNB111

Cat.No. Product Name Price
SHH344128 shRNA set against Human MPZL2 (NM_005797.3) Inquiry
SHG212703 shRNA set against Rat LOC498335(NM_001017496.1) Inquiry
SHH040709 shRNA set against Mouse Eva1(NM_007962.4) Inquiry
SHH344132 shRNA set against Mouse MPZL2 (NM_007962.4) Inquiry
SHH344136 shRNA set against Rat MPZL2 (NM_001106818.1) Inquiry
SHW003509 shRNA set against Chicken MPZL2 (NM_001252284) Inquiry
SHW017919 shRNA set against Danio rerio MPZL2B (NM_212763) Inquiry
Cat.No. Product Name Price
CDFG022249 Mouse Mpzl2 cDNA Clone(BC015076) Inquiry
CDFR006544 Rat Mpzl2 cDNA Clone(NM_001106818.1) Inquiry
MiUTR1M-04503 MPZL2 miRNA 3'UTR clone Inquiry
MiUTR3H-07150 MPZL2 miRNA 3'UTR clone Inquiry
MiUTR3H-07151 MPZL2 miRNA 3'UTR clone Inquiry
CDCB159699 Human MPZL2 ORF clone (BC017774) Inquiry
CDCB164984 Chicken MPZL2 ORF Clone (NM_001252284) Inquiry
CDCB179394 Danio rerio MPZL2B ORF Clone (NM_212763) Inquiry
CDCB184378 Rabbit MPZL2 ORF clone (XM_008249433.1) Inquiry
CDCR373556 Rat Mpzl2 ORF Clone(NM_001106818.1) Inquiry
CDCS412427 Human MPZL2 ORF Clone (BC017774) Inquiry
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