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EP300


Official Full Name
E1A binding protein p300
Organism
Homo sapiens
Gene ID
2033
Background
This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008]
Synonyms
p300; KAT3B; MKHK2; RSTS2

Cat.No. Product Name Price
LV11793L human EP300 (NM_001429) lentivirus particles Inquiry
Cat.No. Product Name Price
SHH286141 shRNA set against Human EP300 (NM_001429.3) Inquiry
SHH286145 shRNA set against Mouse EP300 (NM_177821.6) Inquiry
SHH035083 shRNA set against Mouse Ep300(NM_177821.6) Inquiry
Cat.No. Product Name Price
CDFL004159 Mouse Ep300 cDNA Clone(NM_177821.6) Inquiry
MiUTR1M-04417 EP300 miRNA 3'UTR clone Inquiry
MiUTR3H-05241 EP300 miRNA 3'UTR clone Inquiry
SKO0154 EP300 Validated sgRNA vector Inquiry
CDCB185449 Rabbit EP300 ORF clone (XM_002721395.2) Inquiry
CDCH018574 Human EP300 ORF clone(NM_001429.3) Inquiry
CDCR274410 Mouse Ep300 ORF Clone(NM_177821.6) Inquiry
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