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EML4


Official Full Name
EMAP like 4
Organism
Homo sapiens
Gene ID
27436
Background
This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants. [provided by RefSeq, Jan 2015]
Synonyms
C2orf2; ELP120; EMAP-4; EMAPL4; ROPP120

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