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EIF2S2

Official Full Name
eukaryotic translation initiation factor 2 subunit beta
Organism
Homo sapiens
GeneID
8894
Background
Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Synonyms
EIF2; EIF2B; PPP1R67; EIF2beta; eIF-2-beta;

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