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EDN3


Official Full Name
endothelin 3
Organism
Homo sapiens
Gene ID
1908
Background
The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
Synonyms
ET3; ET-3; WS4B; HSCR4; PPET3

Cat.No. Product Name Price
SHH024221 shRNA set against Human EDN3(NM_207033.1) Inquiry
SHH024225 shRNA set against Human EDN3(NM_000114.2) Inquiry
SHH024243 shRNA set against Human EDN3(NM_207033.1) Inquiry
SHH024257 shRNA set against Human EDN3(NM_207032.1) Inquiry
SHH024275 shRNA set against Rat Edn3(NM_001077650.1) Inquiry
SHH024293 shRNA set against Mouse Edn3(NM_007903.3) Inquiry
SHH283197 shRNA set against Human EDN3 (NM_000114.2) Inquiry
SHH283201 shRNA set against Mouse EDN3 (NM_007903.3) Inquiry
Cat.No. Product Name Price
CDCB160007 Human EDN3 ORF clone (BC008876) Inquiry
MiUTR1M-04173 EDN3 miRNA 3'UTR clone Inquiry
MiUTR1H-03111 EDN3 miRNA 3'UTR clone Inquiry
MiUTR1H-03110 EDN3 miRNA 3'UTR clone Inquiry
MiUTR1H-03109 EDN3 miRNA 3'UTR clone Inquiry
CDFR004994 Rat Edn3 cDNA Clone(NM_001077650.1) Inquiry
CDFH005654 Human EDN3 cDNA Clone(NM_000114.2) Inquiry
CDFG013730 Human EDN3 cDNA Clone(NM_207034.1) Inquiry
CDFG013729 Human EDN3 cDNA Clone(NM_207033.1) Inquiry
CDFG013728 Human EDN3 cDNA Clone(NM_207032.1) Inquiry
CDCR372070 Rat Edn3 ORF Clone(NM_001077650.1) Inquiry
CDCR327837 Human EDN3 ORF Clone(NM_207033.1) Inquiry
MiUTR1R-01647 EDN3 miRNA 3'UTR clone Inquiry
MiUTR3H-00732 EDN3 miRNA 3'UTR clone Inquiry
CDCS405430 Human EDN3 ORF Clone (BC008876) Inquiry
CDCR327840 Human EDN3 ORF Clone(NM_207034.1) Inquiry
CDCR278426 Human EDN3 ORF Clone(NM_000114.2) Inquiry
CDCR244516 Mouse Edn3 ORF Clone(NM_007903.3) Inquiry
CDCR058690 Human EDN3 ORF clone (NM_207032.1) Inquiry
CDCB188670 Rabbit EDN3 ORF clone (XM_008248827.1) Inquiry
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