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EDN1

Official Full Name
endothelin 1
Organism
Homo sapiens
GeneID
1906
Background
This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Synonyms
ET1; QME; PPET1; ARCND3; HDLCQ7;

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