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DUSP5


Official Full Name
dual specificity phosphatase 5
Organism
Homo sapiens
Gene ID
1847
Background
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus. [provided by RefSeq, Jul 2008]
Synonyms
DUSP; HVH3

Cat.No. Product Name Price
SHH019379 shRNA set against Rat Dusp5(NM_133578.1) Inquiry
SHH019397 shRNA set against Human DUSP5(NM_004419.3) Inquiry
SHH281885 shRNA set against Human DUSP5 (NM_004419.3) Inquiry
SHH281889 shRNA set against Mouse DUSP5 (NM_001085390.1) Inquiry
SHH281893 shRNA set against Rat DUSP5 (NM_133578.1) Inquiry
SHW017731 shRNA set against Danio rerio DUSP5 (NM_212565) Inquiry
Cat.No. Product Name Price
CDFH005493 Human DUSP5 cDNA Clone(NM_004419.3) Inquiry
CDFH005494 Human DUSP5 cDNA Clone(NM_004419.3) Inquiry
CDFR014094 Rat Dusp5 cDNA Clone(NM_133578.1) Inquiry
MiUTR1H-03041 DUSP5 miRNA 3'UTR clone Inquiry
MiUTR1R-01614 DUSP5 miRNA 3'UTR clone Inquiry
CDCB179206 Danio rerio DUSP5 ORF Clone (NM_212565) Inquiry
CDCB191819 Rabbit DUSP5 ORF clone (XM_002718707.2) Inquiry
CDCR057828 Human DUSP5 ORF clone (NM_004419.3) Inquiry
CDCR057834 Mouse Dusp5 ORF clone (NM_001085390.1) Inquiry
CDCR381149 Rat Dusp5 ORF Clone(NM_133578.1) Inquiry
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