Pages
Products

DENND5A


Official Full Name
DENN domain containing 5A
Organism
Homo sapiens
Gene ID
23258
Background
This gene encodes a DENN-domain-containing protein that functions as a RAB-activating guanine nucleotide exchange factor (GEF). This protein catalyzes the conversion of GDP to GTP and thereby converts inactive GDP-bound Rab proteins into their active GTP-bound form. The encoded protein is recruited by RAB6 onto Golgi membranes and is therefore referred to as RAB6-interacting protein 1. This protein binds with RAB39 as well. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this gene are associated with early infantile epileptic encephalopathy-49. [provided by RefSeq, Feb 2017]
Synonyms
DEE49; EIEE49; RAB6IP1

Cat.No. Product Name Price
SHH277109 shRNA set against Human DENND5A (NM_015213.3) Inquiry
SHH277113 shRNA set against Rat DENND5A (NM_001107546.2) Inquiry
Cat.No. Product Name Price
CDFR007232 Rat Dennd5a cDNA Clone(NM_001107546.2) Inquiry
MiUTR1M-09863 DENND5A miRNA 3'UTR clone Inquiry
MiUTR3H-14641 DENND5A miRNA 3'UTR clone Inquiry
CDCB187669 Rabbit DENND5A ORF clone (XM_008265965.1) Inquiry
CDCR374113 Rat Dennd5a ORF Clone(NM_001107546.2) Inquiry
CDCS409852 Human DENND5A ORF Clone (BC009354) Inquiry
Quick Inquiry