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DUSP11


Official Full Name
dual specificity phosphatase 11
Organism
Homo sapiens
Gene ID
8446
Background
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism. [provided by RefSeq, Sep 2008]
Synonyms
PIR1

Cat.No. Product Name Price
SHH281689 shRNA set against Mouse DUSP11 (NM_028099.4) Inquiry
SHH018533 shRNA set against Rat Dusp11(NM_001025650.1) Inquiry
SHH281685 shRNA set against Human DUSP11 (NM_003584.2) Inquiry
SHH281693 shRNA set against Rat DUSP11 (NM_001025650.1) Inquiry
SHW008363 shRNA set against Danio rerio DUSP11 (NM_001017722) Inquiry
Cat.No. Product Name Price
CDFH005479 Human DUSP11 cDNA Clone(NM_003584.2) Inquiry
CDFR004007 Rat Dusp11 cDNA Clone(NM_001025650.1) Inquiry
MiUTR1R-01608 DUSP11 miRNA 3'UTR clone Inquiry
MiUTR3H-05658 DUSP11 miRNA 3'UTR clone Inquiry
CDCB169838 Danio rerio DUSP11 ORF Clone (NM_001017722) Inquiry
CDCB186885 Rabbit DUSP11 ORF clone (XM_008254237.1) Inquiry
CDCR057714 Human DUSP11 ORF clone (NM_003584.2) Inquiry
CDCR370982 Rat Dusp11 ORF Clone(NM_001025650.1) Inquiry
CDCS411365 Human DUSP11 ORF Clone (BC000346) Inquiry
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