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DCTN2


Official Full Name
dynactin subunit 2
Organism
Homo sapiens
Gene ID
10540
Background
This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2012]
Synonyms
RBP50; DCTN50; HEL-S-77; DYNAMITIN

Cat.No. Product Name Price
SHW005308 shRNA set against Chicken DCTN2 (NM_204802) Inquiry
SHG224679 shRNA set against Rat Dctn2(NM_001004239.1) Inquiry
SHH275369 shRNA set against Human DCTN2 (NM_006400.4) Inquiry
SHH275373 shRNA set against Mouse DCTN2 (NM_027151.2) Inquiry
SHH275377 shRNA set against Rat DCTN2 (NM_001004239.1) Inquiry
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Cat.No. Product Name Price
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MiUTR3H-09181 DCTN2 miRNA 3'UTR clone Inquiry
CDCB158927 Human DCTN2 ORF clone (BC000718) Inquiry
CDCB166783 Chicken DCTN2 ORF Clone (NM_204802) Inquiry
CDCB178744 Danio rerio DCTN2 ORF Clone (NM_201166) Inquiry
CDCB194123 Rabbit DCTN2 ORF clone (XM_002720918.2) Inquiry
CDCR054066 Mouse Dctn2 ORF clone (NM_001190453.1) Inquiry
CDCR243171 Mouse Dctn2 ORF Clone(NM_001190454.1) Inquiry
CDCR259840 Mouse Dctn2 ORF Clone(NM_027151.2) Inquiry
CDCR368437 Rat Dctn2 ORF Clone(NM_001004239.1) Inquiry
CDCS412716 Human DCTN2 ORF Clone (BC000718) Inquiry
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