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DBT


Official Full Name
dihydrolipoamide branched chain transacylase E2
Organism
Homo sapiens
Gene ID
1629
Background
The branched-chain alpha-keto acid dehydrogenase complex (BCKD) is an inner-mitochondrial enzyme complex involved in the breakdown of the branched-chain amino acids isoleucine, leucine, and valine. The BCKD complex is thought to be composed of a core of 24 transacylase (E2) subunits, and associated decarboxylase (E1), dehydrogenase (E3), and regulatory subunits. This gene encodes the transacylase (E2) subunit. Mutations in this gene result in maple syrup urine disease, type 2. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Synonyms
E2; E2B; BCATE2; BCKADE2; BCKAD-E2; BCKDH-E2; BCOADC-E2

Cat.No. Product Name Price
SHH274817 shRNA set against Human DBT (NM_001918.3) Inquiry
SHH274825 shRNA set against Rat DBT (NM_053312.1) Inquiry
SHW008069 shRNA set against Danio rerio DBT (NM_001013515) Inquiry
SHH274821 shRNA set against Mouse DBT (NM_010022.3) Inquiry
SHW005167 shRNA set against Chicken DBT (NM_204656) Inquiry
Cat.No. Product Name Price
CDCH384969 Human DBT ORF clone(NM_001918.3) Inquiry
CDFR013069 Rat Dbt cDNA Clone(NM_053312.1) Inquiry
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CDCB166642 Chicken DBT ORF Clone (NM_204656) Inquiry
CDCB169544 Danio rerio DBT ORF Clone (NM_001013515) Inquiry
CDCB189621 Rabbit DBT ORF clone (XM_002715835.2) Inquiry
CDCH384970 Mouse DBT ORF clone(NM_010022.3) Inquiry
CDCR380116 Rat Dbt ORF Clone(NM_053312.1) Inquiry
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