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DAP3


Official Full Name
death associated protein 3
Organism
Homo sapiens
Gene ID
7818
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q. [provided by RefSeq, Dec 2010]
Synonyms
mS29; DAP-3; S29mt; MRPS29; MRP-S29; bMRP-10

Cat.No. Product Name Price
SHH274525 shRNA set against Mouse DAP3 (NM_022994.3) Inquiry
SHH274529 shRNA set against Rat DAP3 (NM_001011950.2) Inquiry
SHH274521 shRNA set against Human DAP3 (NM_004632.3) Inquiry
SHW011587 shRNA set against Danio rerio DAP3 (NM_001098737) Inquiry
Cat.No. Product Name Price
CDFR002380 Rat Dap3 cDNA Clone(NM_001011950.2) Inquiry
MiUTR3H-04645 DAP3 miRNA 3'UTR clone Inquiry
MiUTR3H-04646 DAP3 miRNA 3'UTR clone Inquiry
CDCB157881 Human DAP3 ORF clone (BC107488) Inquiry
CDCB173062 Danio rerio DAP3 ORF Clone (NM_001098737) Inquiry
CDCB185945 Rabbit DAP3 ORF clone (XM_002715415.2) Inquiry
CDCH384925 Mouse DAP3 ORF clone(NM_022994.3) Inquiry
CDCR053436 Human DAP3 ORF clone (NM_001199851.1) Inquiry
CDCR053443 Mouse Dap3 ORF clone (NM_001164533.1) Inquiry
CDCR053444 Human DAP3 ORF clone (NM_001199850.1) Inquiry
CDCR369467 Rat Dap3 ORF Clone(NM_001011950.2) Inquiry
CDCS409501 Human DAP3 ORF Clone (BC107488) Inquiry
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