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CYTH2


Official Full Name
cytohesin 2
Organism
Homo sapiens
Gene ID
9266
Background
The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Synonyms
ARNO; CTS18; PSCD2; SEC7L; PSCD2L; CTS18.1; Sec7p-L; Sec7p-like; cytohesin-2

Cat.No. Product Name Price
SHH273917 shRNA set against Human CYTH2 (NM_004228.6) Inquiry
SHH273921 shRNA set against Mouse CYTH2 (NM_011181.3) Inquiry
SHH273925 shRNA set against Rat CYTH2 (NM_053911.2) Inquiry
Cat.No. Product Name Price
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CDCR287495 Human CYTH2 ORF Clone(NM_004228.6) Inquiry
CDCR380658 Rat Cyth2 ORF Clone(NM_053911.2) Inquiry
CDCS411683 Human CYTH2 ORF Clone (BC004361) Inquiry
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