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COQ6


Official Full Name
coenzyme Q6, monooxygenase
Organism
Homo sapiens
Gene ID
51004
Background
The protein encoded by this gene belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 (or ubiquinone), which is an essential component of the mitochondrial electron transport chain, and one of the most potent lipophilic antioxidants implicated in the protection of cell damage by reactive oxygen species. Knockdown of this gene in mouse and zebrafish results in decreased growth due to increased apoptosis. Mutations in this gene are associated with autosomal recessive coenzyme Q10 deficiency-6 (COQ10D6), which manifests as nephrotic syndrome with sensorineural deafness. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2012]
Synonyms
CGI10; CGI-10; COQ10D6

Cat.No. Product Name Price
SHW010253 shRNA set against Danio rerio COQ6 (NM_001045404) Inquiry
SHG193255 shRNA set against Rat Coq6(NM_001011983.1) Inquiry
SHH267997 shRNA set against Human COQ6 (NM_182480.2) Inquiry
SHH268001 shRNA set against Mouse COQ6 (NM_172582.3) Inquiry
SHH268005 shRNA set against Rat COQ6 (NM_001011983.1) Inquiry
Cat.No. Product Name Price
CDCS418366 Human COQ6 ORF Clone (BC014181) Inquiry
CDCS418367 Human COQ6 ORF Clone (BC014483) Inquiry
CDFR002412 Rat Coq6 cDNA Clone(NM_001011983.1) Inquiry
MiUTR1R-01129 COQ6 miRNA 3'UTR clone Inquiry
MiUTR3H-13335 COQ6 miRNA 3'UTR clone Inquiry
MiUTR3H-13336 COQ6 miRNA 3'UTR clone Inquiry
CDCB156290 Cynomolgus COQ6 ORF clone (XM_005561747.1) Inquiry
CDCB160368 Human COQ6 ORF clone (NM_182476.1) Inquiry
CDCB171728 Danio rerio COQ6 ORF Clone (NM_001045404) Inquiry
CDCB192429 Rabbit COQ6 ORF clone (XM_002719654.2) Inquiry
CDCR271247 Mouse Coq6 ORF Clone(NM_172582.3) Inquiry
CDCR369500 Rat Coq6 ORF Clone(NM_001011983.1) Inquiry
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