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CLDN5

Official Full Name
claudin 5
Organism
Homo sapiens
GeneID
7122
Background
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2018]
Synonyms
AWAL; BEC1; TMVCF; TMDVCF; CPETRL1;

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