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CCNT1


Official Full Name
cyclin T1
Organism
Homo sapiens
Gene ID
904
Background
This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of this gene is implicated in tumor growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
Synonyms
CCNT; CYCT1; HIVE1

Cat.No. Product Name Price
SHG152745 shRNA set against Mouse Ccnt1(NM_009833.1) Inquiry
SHH258041 shRNA set against Human Ccnt1 (NM_001240.3) Inquiry
SHH258045 shRNA set against Mouse Ccnt1 (NM_009833.1) Inquiry
SHH258049 shRNA set against Rat Ccnt1 (NM_001108110.1) Inquiry
SHW014054 shRNA set against Danio rerio CCNT1 (NM_001256611) Inquiry
Cat.No. Product Name Price
CDCR374802 Rat Ccnt1 ORF Clone(NM_001108110.1) Inquiry
CDFL002378 Mouse Ccnt1 cDNA Clone(NM_009833.1) Inquiry
CDFR007775 Rat Ccnt1 cDNA Clone(NM_001108110.1) Inquiry
MiUTR1M-02703 CCNT1 miRNA 3'UTR clone Inquiry
MiUTR3H-01122 CCNT1 miRNA 3'UTR clone Inquiry
CDCB175529 Danio rerio CCNT1 ORF Clone (NM_001256611) Inquiry
CDCB186590 Rabbit CCNT1 ORF clone (XM_002711000.2) Inquiry
CDCR043624 Mouse Ccnt1 ORF clone (NM_009833.1) Inquiry
CDCR280317 Human CCNT1 ORF Clone(NM_001240.3) Inquiry
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