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CCNH


Official Full Name
cyclin H
Organism
Homo sapiens
Gene ID
902
Background
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Nov 2010]
Synonyms
CAK; p34; p37; CycH

Cat.No. Product Name Price
SHH257945 shRNA set against Mouse CCNH (NM_023243.5) Inquiry
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SHH257941 shRNA set against Human CCNH (NM_001239.3) Inquiry
SHH257949 shRNA set against Rat CCNH (NM_052981.2) Inquiry
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Cat.No. Product Name Price
CDCB169504 Danio rerio CCNH ORF Clone (NM_001013453) Inquiry
CDCR380089 Rat Ccnh ORF Clone(NM_052981.2) Inquiry
CDCS409436 Human CCNH ORF Clone (BC005280) Inquiry
CDFR013042 Rat Ccnh cDNA Clone(NM_052981.2) Inquiry
MiUTR1M-02697 CCNH miRNA 3'UTR clone Inquiry
MiUTR1R-00814 CCNH miRNA 3'UTR clone Inquiry
MiUTR3H-04526 CCNH miRNA 3'UTR clone Inquiry
CDCB182532 Rabbit CCNH ORF clone (XM_002713905.2) Inquiry
CDCL183142 Mouse CCNH ORF clone(NM_023243.5) Inquiry
CDCR043564 Human CCNH ORF clone (NM_001199189.1) Inquiry
CDCS409435 Human CCNH ORF Clone (BC016705) Inquiry
CDCS409437 Human CCNH ORF Clone (BC022351) Inquiry
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