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CBS


Official Full Name
cystathionine beta-synthase
Organism
Homo sapiens
Gene ID
875
Background
The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2016]
Synonyms
CBSL; HIP4

Cat.No. Product Name Price
SHH255445 shRNA set against Human CBS (NM_000071.2) Inquiry
SHH255453 shRNA set against Rat CBS (NM_012522.2) Inquiry
SHG145136 shRNA set against Rat Cbs(NM_012522.2) Inquiry
SHH255449 shRNA set against Mouse CBS (NM_178224.3) Inquiry
SHW008152 shRNA set against Danio rerio CBSB (NM_001014345) Inquiry
Cat.No. Product Name Price
CDCS405396 Human CBS ORF Clone (BC007257) Inquiry
MiUTR1R-00771 CBS miRNA 3'UTR clone Inquiry
CDFR010199 Rat Cbs cDNA Clone(NM_012522.2) Inquiry
CDFH002799 Human CBS cDNA Clone(NM_001178009.1) Inquiry
CDFH002798 Human CBS cDNA Clone(NM_001178008.1) Inquiry
MiUTR3H-12872 CBS miRNA 3'UTR clone Inquiry
SKO0358 CBS Validated sgRNA vector Inquiry
CDCB169627 Danio rerio CBSB ORF Clone (NM_001014345) Inquiry
CDCR377430 Rat Cbs ORF Clone(NM_012522.2) Inquiry
CDCR357193 Human CBS ORF Clone(NM_001178008.1) Inquiry
CDCS405397 Human CBS ORF Clone (BC000440) Inquiry
CDCS405398 Human CBS ORF Clone (BC010242) Inquiry
CDCR274694 Mouse Cbs ORF Clone(NM_178224.3) Inquiry
CDCG012870 Mouse CBS ORF clone(NM_144855.3) Inquiry
CDCB195617 Rabbit CBS ORF clone (NM_001082082.2) Inquiry
CDCR357194 Human CBS ORF Clone(NM_001178009.1) Inquiry
CDCB159217 Human CBS ORF clone (BC000440) Inquiry
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