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CACNA1B

Official Full Name
calcium voltage-gated channel subunit alpha1 B
Organism
Homo sapiens
GeneID
774
Background
The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Synonyms
BIII; CACNN; DYT23; Cav2.2; NEDNEH; CACNL1A5;

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