Pages
Products

CRYBB3


Official Full Name
crystallin beta B3
Organism
Homo sapiens
Gene ID
1417
Background
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta basic group member, is part of a gene cluster with beta-A4, beta-B1, and beta-B2. Mutations in this gene result in cataract congenital nuclear autosomal recessive type 2. [provided by RefSeq, Feb 2013]
Synonyms
CRYB3; CATCN2; CTRCT22

Cat.No. Product Name Price
SHG201301 shRNA set against Human CRYBB3(NM_004076.3) Inquiry
SHG201373 shRNA set against Rat Crybb3(NM_031690.1) Inquiry
SHH269981 shRNA set against Human CRYBB3 (NM_004076.3) Inquiry
SHH269985 shRNA set against Mouse CRYBB3 (NM_021352.3) Inquiry
SHH269989 shRNA set against Rat CRYBB3 (NM_031690.1) Inquiry
SHW005688 shRNA set against Chicken CRYBB3 (NM_205191) Inquiry
SHW008530 shRNA set against Danio rerio CRYBB3 (NM_001018130) Inquiry
Cat.No. Product Name Price
CDFH004294 Human CRYBB3 cDNA Clone(NM_004076.3) Inquiry
CDFR012826 Rat Crybb3 cDNA Clone(NM_031690.1) Inquiry
MiUTR1H-02448 CRYBB3 miRNA 3'UTR clone Inquiry
MiUTR1R-01203 CRYBB3 miRNA 3'UTR clone Inquiry
CDCB167163 Chicken CRYBB3 ORF Clone (NM_205191) Inquiry
CDCB170005 Danio rerio CRYBB3 ORF Clone (NM_001018130) Inquiry
CDCB187468 Rabbit CRYBB3 ORF clone (XM_008249121.1) Inquiry
CDCH384180 Mouse CRYBB3 ORF clone(NM_021352.3) Inquiry
CDCR050896 Human CRYBB3 ORF clone (NM_004076.3) Inquiry
CDCR238740 Mouse Crybb3 ORF Clone(NM_001159650.1) Inquiry
CDCR379840 Rat Crybb3 ORF Clone(NM_031690.1) Inquiry
CDCS411595 Human CRYBB3 ORF Clone (BC102022) Inquiry
Quick Inquiry