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CRK


Official Full Name
CRK proto-oncogene, adaptor protein
Organism
Homo sapiens
Gene ID
1398
Background
This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008]
Synonyms
p38; CRKII

Cat.No. Product Name Price
SHG199735 shRNA set against Rat Crk(NM_019302.1) Inquiry
SHH269637 shRNA set against Human CRK (NM_016823.3) Inquiry
SHH269641 shRNA set against Mouse CRK (NM_133656.4) Inquiry
SHH269645 shRNA set against Rat CRK (NM_019302.1) Inquiry
SHW000713 shRNA set against Chicken CRK (NM_001007846) Inquiry
SHW006939 shRNA set against Danio rerio CRK (NM_001003628) Inquiry
Cat.No. Product Name Price
CDFR011394 Rat Crk cDNA Clone(NM_019302.1) Inquiry
MiUTR1R-01182 CRK miRNA 3'UTR clone Inquiry
MiUTR3H-01596 CRK miRNA 3'UTR clone Inquiry
MiUTR3H-01597 CRK miRNA 3'UTR clone Inquiry
CDCB160315 Human CRK ORF clone (NM_016823.2) Inquiry
CDCB162188 Chicken CRK ORF Clone (NM_001007846) Inquiry
CDCB168414 Danio rerio CRK ORF Clone (NM_001003628) Inquiry
CDCB182762 Rabbit CRK ORF clone (XM_002718889.2) Inquiry
CDCH384134 Mouse CRK ORF clone(NM_133656.4) Inquiry
CDCR378596 Rat Crk ORF Clone(NM_019302.1) Inquiry
CDCS412140 Human CRK ORF Clone (BC009837) Inquiry
CDCS412141 Human CRK ORF Clone (BC008506) Inquiry
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