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COPS5


Official Full Name
COP9 signalosome subunit 5
Organism
Homo sapiens
Gene ID
10987
Background
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq, Jul 2008]
Synonyms
CSN5; JAB1; SGN5; MOV-34

Cat.No. Product Name Price
SHG192727 shRNA set against Rat Cops5(NM_001025695.1) Inquiry
SHG192787 shRNA set against Human COPS5(NM_006837.2) Inquiry
SHG192823 shRNA set against Mouse Cops5(NM_013715.1) Inquiry
SHH267829 shRNA set against Human COPS5 (NM_006837.2) Inquiry
SHH267833 shRNA set against Mouse COPS5 (NM_013715.1) Inquiry
SHH267837 shRNA set against Rat COPS5 (NM_001025695.1) Inquiry
SHW002312 shRNA set against Chicken COPS5 (NM_001039311) Inquiry
SHW016875 shRNA set against Danio rerio COPS5 (NM_200725) Inquiry
Cat.No. Product Name Price
CDCR049634 Mouse Cops5 ORF clone (NM_013715.1) Inquiry
CDCR293786 Human COPS5 ORF Clone(NM_006837.2) Inquiry
CDFH004088 Human COPS5 cDNA Clone(NM_006837.2) Inquiry
CDFH004089 Human COPS5 cDNA Clone(NM_006837.2) Inquiry
CDFR004051 Rat Cops5 cDNA Clone(NM_001025695.1) Inquiry
MiUTR1H-02359 COPS5 miRNA 3'UTR clone Inquiry
MiUTR1M-03235 COPS5 miRNA 3'UTR clone Inquiry
CDCB163787 Chicken COPS5 ORF Clone (NM_001039311) Inquiry
CDCB178350 Danio rerio COPS5 ORF Clone (NM_200725) Inquiry
CDCB190966 Rabbit COPS5 ORF clone (XM_002710454.2) Inquiry
CDCR371026 Rat Cops5 ORF Clone(NM_001025695.1) Inquiry
CDCS412939 Human COPS5 ORF Clone (BC001187) Inquiry
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