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CHM


Official Full Name
CHM Rab escort protein
Organism
Homo sapiens
Gene ID
1121
Background
This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia; also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]
Synonyms
TCD; GGTA; REP-1; DXS540; HSD-32

Cat.No. Product Name Price
SHH263141 shRNA set against Human CHM (NM_000390.2) Inquiry
SHH263149 shRNA set against Rat CHM (NM_017067.1) Inquiry
SHG175375 shRNA set against Human CHM(NM_000390.2) Inquiry
SHG175411 shRNA set against Mouse Chm(NM_018818.2) Inquiry
SHG175429 shRNA set against Rat Chm(NM_017067.1) Inquiry
SHH263145 shRNA set against Mouse CHM (NM_018818.2) Inquiry
SHW001733 shRNA set against Chicken CHM (NM_001031119) Inquiry
SHW017463 shRNA set against Danio rerio CHM (NM_203461) Inquiry
Cat.No. Product Name Price
CDFH003613 Human CHM cDNA Clone(NM_001145414.1) Inquiry
CDFL002680 Mouse Chm cDNA Clone(NM_018818.2) Inquiry
CDFR011134 Rat Chm cDNA Clone(NM_017067.1) Inquiry
MiUTR1H-02122 CHM miRNA 3'UTR clone Inquiry
MiUTR1M-03003 CHM miRNA 3'UTR clone Inquiry
MiUTR1R-00968 CHM miRNA 3'UTR clone Inquiry
CDCB163208 Chicken CHM ORF Clone (NM_001031119) Inquiry
CDCB178938 Danio rerio CHM ORF Clone (NM_203461) Inquiry
CDCB181332 Rabbit CHM ORF clone (XM_008272993.1) Inquiry
CDCR046782 Human CHM ORF clone (NM_001145414.1) Inquiry
CDCR046792 Mouse Chm ORF clone (NM_018818.2) Inquiry
CDCR336087 Human CHM ORF Clone(NM_000390.2) Inquiry
CDCR378167 Rat Chm ORF Clone(NM_017067.1) Inquiry
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