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CDC45


Official Full Name
cell division cycle 45
Organism
Homo sapiens
Gene ID
8318
Background
The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Synonyms
CDC45L; MGORS7; CDC45L2; PORC-PI-1

Cat.No. Product Name Price
SHG161965 shRNA set against Human CDC45L(NM_003504.3) Inquiry
SHH259941 shRNA set against Human CDC45 (NM_003504.3) Inquiry
SHH259945 shRNA set against Mouse CDC45 (NM_009862.2) Inquiry
SHH259949 shRNA set against Rat CDC45 (NM_001105866.2) Inquiry
SHW018449 shRNA set against Danio rerio CDC45 (NM_213386) Inquiry
Cat.No. Product Name Price
CDCR044962 Mouse Cdc45l ORF clone (NM_001161623.1) Inquiry
CDFG020061 Mouse Cdc45 cDNA Clone(NM_001161623.1) Inquiry
CDFH003234 Human CDC45 cDNA Clone(NM_001178011.1) Inquiry
CDFH003235 Human CDC45 cDNA Clone(NM_001178010.1) Inquiry
CDFH003236 Human CDC45 cDNA Clone(NM_003504.3) Inquiry
CDFR005594 Rat Cdc45 cDNA Clone(NM_001105866.2) Inquiry
MiUTR1H-01963 CDC45 miRNA 3'UTR clone Inquiry
CDCB179924 Danio rerio CDC45 ORF Clone (NM_213386) Inquiry
CDCB186838 Rabbit CDC45 ORF clone (XM_008252120.1) Inquiry
CDCR044954 Human CDC45 ORF clone (NM_003504.3) Inquiry
CDCR044956 Human CDC45 ORF clone (NM_001178010.1) Inquiry
CDCR044958 Human CDC45 ORF clone (NM_001178011.1) Inquiry
CDCR372682 Rat Cdc45 ORF Clone(NM_001105866.2) Inquiry
CDCS418294 Human CDC45 ORF Clone (BC006232) Inquiry
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