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CD59


Official Full Name
CD59 molecule (CD59 blood group)
Organism
Homo sapiens
Gene ID
966
Background
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
Synonyms
1F5; EJ16; EJ30; EL32; G344; MIN1; MIN2; MIN3; MIRL; HRF20; MACIF; MEM43; MIC11; MSK21; 16.3A5; HRF-20; MAC-IP; p18-20

Cat.No. Product Name Price
SHG158052 shRNA set against Rat Cd59(NM_012925.1) Inquiry
SHH259225 shRNA set against Human CD59 (NM_000611.5) Inquiry
SHH259229 shRNA set against Mouse CD59 (NM_181858.1) Inquiry
SHH259233 shRNA set against Rat CD59 (NM_012925.1) Inquiry
Cat.No. Product Name Price
CDFH003142 Human CD59 cDNA Clone(NM_001127226.1) Inquiry
MiUTR1H-01897 CD59 miRNA 3'UTR clone Inquiry
MiUTR1H-01896 CD59 miRNA 3'UTR clone Inquiry
MiUTR1H-01895 CD59 miRNA 3'UTR clone Inquiry
MiUTR1H-01894 CD59 miRNA 3'UTR clone Inquiry
MiUTR1H-01893 CD59 miRNA 3'UTR clone Inquiry
MiUTR1H-01892 CD59 miRNA 3'UTR clone Inquiry
CDFR010766 Rat Cd59 cDNA Clone(NM_012925.1) Inquiry
CDFH003143 Human CD59 cDNA Clone(NM_001127227.1) Inquiry
MiUTR1H-01898 CD59 miRNA 3'UTR clone Inquiry
MiUTR1R-00852 CD59 miRNA 3'UTR clone Inquiry
CDFH003140 Human CD59 cDNA Clone(NM_001127223.1) Inquiry
CDCR348562 Human CD59 ORF Clone(NM_001127225.1) Inquiry
CDCR348560 Human CD59 ORF Clone(NM_001127223.1) Inquiry
CDFH003141 Human CD59 cDNA Clone(NM_001127225.1) Inquiry
CDCS405791 Human CD59 ORF Clone (BC001506) Inquiry
CDCR348566 Human CD59 ORF Clone(NM_001127227.1) Inquiry
CDCR348564 Human CD59 ORF Clone(NM_001127226.1) Inquiry
CDCL183372 Rat CD59 ORF clone(NM_012925.1) Inquiry
CDCB180709 Rabbit CD59 ORF clone (XM_008268549.1) Inquiry
CDCB156681 Cynomolgus CD59 ORF clone Inquiry
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