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BCL10


Official Full Name
BCL10 immune signaling adaptor
Organism
Homo sapiens
Gene ID
8915
Background
This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Synonyms
CLAP; mE10; CIPER; IMD37; c-E10; CARMEN

Cat.No. Product Name Price
SHW003438 shRNA set against Chicken BCL10 (NM_001201487) Inquiry
SHG096713 shRNA set against Rat Bcl10(NM_031328.1) Inquiry
SHG096757 shRNA set against Mouse Bcl10(NM_009740.1) Inquiry
SHH245846 shRNA set against Human BCL10 (NM_003921.4) Inquiry
SHH245850 shRNA set against Mouse BCL10 (NM_009740.1) Inquiry
SHH245854 shRNA set against Rat BCL10 (NM_031328.1) Inquiry
Cat.No. Product Name Price
CDFR012633 Rat Bcl10 cDNA Clone(NM_031328.1) Inquiry
MiUTR1M-02152 BCL10 miRNA 3'UTR clone Inquiry
MiUTR1R-00533 BCL10 miRNA 3'UTR clone Inquiry
MiUTR3H-06045 BCL10 miRNA 3'UTR clone Inquiry
SKO0331 BCL10 Validated sgRNA vector Inquiry
SKO0953 BCL10 Validated sgRNA vector Inquiry
CDCB164913 Chicken BCL10 ORF Clone (NM_001201487) Inquiry
CDCB184397 Rabbit BCL10 ORF clone (XM_008264952.1) Inquiry
CDCR034064 Mouse Bcl10 ORF clone (NM_009740.1) Inquiry
CDCR379666 Rat Bcl10 ORF Clone(NM_031328.1) Inquiry
CDCS411544 Human BCL10 ORF Clone (BC053617) Inquiry
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