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BAG4


Official Full Name
BAG cochaperone 4
Organism
Homo sapiens
Gene ID
9530
Background
The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
Synonyms
SODD; BAG-4

Cat.No. Product Name Price
SHH244654 shRNA set against Human BAG4 (NM_004874.3) Inquiry
SHG090433 shRNA set against Mouse Bag4(NM_026121.3) Inquiry
SHG090435 shRNA set against Rat Bag4(NM_001025130.1) Inquiry
SHG090453 shRNA set against Human BAG4(NM_004874.3) Inquiry
SHH231630 shRNA set against Mouse Adam34 (NM_145745.2) Inquiry
SHH244658 shRNA set against Mouse BAG4 (NM_026121.3) Inquiry
SHH244662 shRNA set against Rat BAG4 (NM_001025130.1) Inquiry
SHW014080 shRNA set against Danio rerio BAG4 (NM_001256729) Inquiry
Cat.No. Product Name Price
CDCR267639 Mouse Adam34 ORF Clone(NM_145745.2) Inquiry
CDCR370882 Rat Bag4 ORF Clone(NM_001025130.1) Inquiry
CDFR003859 Rat Bag4 cDNA Clone(NM_001025130.1) Inquiry
MiUTR1H-00788 BAG4 miRNA 3'UTR clone Inquiry
MiUTR1M-01959 BAG4 miRNA 3'UTR clone Inquiry
MiUTR1R-00507 BAG4 miRNA 3'UTR clone Inquiry
CDCB175555 Danio rerio BAG4 ORF Clone (NM_001256729) Inquiry
CDCB185981 Rabbit BAG4 ORF clone (XM_002720783.2) Inquiry
CDCR033000 Human BAG4 ORF clone (NM_001204878.1) Inquiry
CDCR033002 Mouse Bag4 ORF clone (NM_026121.3) Inquiry
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