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BBS10


Official Full Name
Bardet-Biedl syndrome 10
Organism
Homo sapiens
Gene ID
79738
Background
This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and cognitive disability. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein's expression impairs ciliogenesis in preadipocytes. Mutations in this gene cause Bardet-Biedl syndrome type 10. [provided by RefSeq, Jan 2010]
Synonyms
C12orf58

Cat.No. Product Name Price
SHH245118 shRNA set against Human BBS10 (NM_024685.3) Inquiry
SHH245122 shRNA set against Mouse BBS10 (NM_027914.1) Inquiry
SHW011458 shRNA set against Danio rerio BBS10 (NM_001089463) Inquiry
Cat.No. Product Name Price
CDCR033340 Mouse Bbs10 ORF clone (NM_027914.1) Inquiry
CDFG004400 Human BBS10 cDNA Clone(NM_024685.3) Inquiry
CDFL001762 Mouse Bbs10 cDNA Clone(NM_027914.1) Inquiry
CDFR008873 Rat Bbs10 cDNA Clone(NM_001109286.1) Inquiry
MiUTR1H-00823 BBS10 miRNA 3'UTR clone Inquiry
CDCB158436 Human BBS10 ORF clone (BC013795) Inquiry
CDCB172933 Danio rerio BBS10 ORF Clone (NM_001089463) Inquiry
CDCB189481 Rabbit BBS10 ORF clone (XM_008256824.1) Inquiry
CDCR033338 Human BBS10 ORF clone (NM_024685.3) Inquiry
CDCR375872 Rat Bbs10 ORF Clone(NM_001109286.1) Inquiry
CDCS418097 Human BBS10 ORF Clone (BC026355) Inquiry
CDCS418098 Human BBS10 ORF Clone (BC013795) Inquiry
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